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TOC Ariake Convention Hall

Mar 26, 2018 9:00 AM - Mar 27, 2018 6:00 PM

3-5-7 Ariake, , Koto-ku, Tokyo, 135-0063 Japan

12th DIA Asia New Drug Conference in Japan

[Session 2] Regulatory and Industry Challenges to ICH E17 Implementation

Session Chair(s)

Yoshiaki  Uyama, PhD, RPh

Yoshiaki Uyama, PhD, RPh

Associate Executive Director

Pharmaceuticals and Medical Devices Agency (PMDA), Japan

At the November 2017 ICH Geneva meeting, the ICH E17 guideline “General Principles for Planning and Design of Multi-Regional Clinical Trials (MRCTs)” was finalized. Promoting multiregional drug development increases the number of regions participating in a MRCT; regional regulatory authorities and industry are being expected to challenge in consistency evaluation between overall and regional results, and sample size allocations to regions. In this session, several regulatory authorities will provide their perspective on current difficulties with not only planning and designing MRCTs but also data interpretation and challenges from implementing this guideline. Panel discussion will exchange various opinions from regulatory authorities and additional industry panelists.

Speaker(s)

Yoshiaki  Uyama, PhD, RPh

Overview of ICH E17

Yoshiaki Uyama, PhD, RPh

Pharmaceuticals and Medical Devices Agency (PMDA), Japan

Associate Executive Director

I-Chun  Lai, MD, MS

T-CDE’s Experiences to Review MRCT Results and Expectations for E17 Guideline

I-Chun Lai, MD, MS

Center for Drug Evaluation, Taiwan

Director, Consultation Division

Mee Ryung  Ahn, PhD

MFDS’s Experiences to Review MRCT Data

Mee Ryung Ahn, PhD

Ministry of Food and Drug Safety, Korea, Republic of

Director

Yoko  Aoi, PhD

PMDA’s Experiences to Review MRCT Results and Expectations for E17 Guideline

Yoko Aoi, PhD

Pharmaceuticals and Medical Devices Agency (PMDA), Japan

Deputy Review Director, Office of New Drug V

Osamu  Komiyama

Osamu Komiyama

Pfizer R&D Japan G.K., Japan

Senior Manager, Statistical Research & Data Science

Yasuto  Otsubo

Yasuto Otsubo

Pharmaceuticals and Medical Devices Agency (PMDA), Japan

Review Director, Office of New Drug II

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