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Walter E. Washington Convention Center

Jun 15, 2025 7:00 AM - Jun 19, 2025 3:00 PM

801 Allen Y. Lew Place, NW, Washington, DC 20001-3614, USA

DIA 2025 Global Annual Meeting

Expanding Innovative Master Protocol Trial Designs to Cell and Gene Therapies for Rare Diseases

Session Chair(s)

Nancy Bradish Myers, JD

Nancy Bradish Myers, JD

CEO and Founder

Catalyst Healthcare Consulting, United States

Master Protocols, including basket trials and umbrella trials, enable efficiencies in investigating multiple conditions or multiple treatments, respectively, under a single trial design. Applying Master Protocol trial designs to Cell & Gene therapies (CGTs) can streamline clinical and regulatory processes to speed the delivery of treatments to patients with rare diseases.

Learning Objective : Identify barriers to and solutions for leveraging Master Protocol clinical trial designs to study Cell & Gene Therapies for rare diseases.

Speaker(s)

Philip (P.J.)  Brooks, PHD

Thought Leader Perspective

Philip (P.J.) Brooks, PHD

National Center for Advancing Translational Sciences (NCATS), NIH, United States

Deputy Director, Division of Rare Diseases Research Innovation

Kiran  Musunuru, MD, PHD, MPH

Innovator Perspective

Kiran Musunuru, MD, PHD, MPH

University of Pennsylvania, United States

Professor of Medicine

Jeff  Allen, PHD

Researcher Perspective

Jeff Allen, PHD

Friends of Cancer Research, United States

President and Chief Executive Officer

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