Walter E. Washington Convention Center

Jun 15, 2025 7:00 AM - Jun 19, 2025 3:00 PM

801 Allen Y. Lew Place, NW, Washington, DC 20001-3614, USA

DIA 2025 Global Annual Meeting

Regulatory and HTA Considerations When Using External Evidence to Support Single Arm Trials During Global Drug Development

Session Chair(s)

Solange  Corriol-Rohou, DrMed, MD, PhD

Solange Corriol-Rohou, DrMed, MD, PhD

Senior Director, Global Regulatory Affairs & Policy, R&D, Europe

AstraZeneca , France

Single Arm Trials (SATs) are an important tool for drug development. The session while focusing on EMA and FDA guidance documents on SATs, will discuss how external information can support the needs and expectations of regulators and HTA globally.

Learning Objective : Identify the appropriate settings and considerations for using external evidence in designing single-arm trials; Discuss strategies for advancing global drug development with single-arm trials, addressing differing perspectives among regulators and between regulators and HTA representatives.

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