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DIA Global Center

2017 年 11 月 09 日 8:15 上午 - 2017 年 11 月 10 日 3:30 下午

21 Dupont Circle NW, Suite 300, Washington, DC 20036

Adaptive Design in Clinical Trials: When and How to Apply

Session 5: Commonly Used Adaptations

Session Chair(s)

Sandeep  Menon, PhD

Sandeep Menon, PhD

Chief Scientific Officer of Artificial Intelligence and Digital Science and SVP,

Pfizer Inc, United States

This session includes a 15 minute refreshment break around 3:00PM

  • Adaptation of Sample Size Based on Interim-Effect Size Estimates
  • Adaptation of Patient Population Based on Treatment-Effect Estimates (or adaptive population enrichment)
  • Adaptation for Dose Selection Studies (at exploratory or confirmatory stage)
  • Adaptive Randomization

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